hs-CRP and inflammatory markers
Reads: Calms body-wide inflammation
They are not one thing: anti-TNF Worsened Heart Failure while IL-1-beta Blockade Reduced Cardiovascular Events. One node cannot carry opposite intervention results.
What this marker reads
Chronic low-grade inflammation in peripheral tissue — vessel wall, myocardium, follicle, joint.
What a named body publishes
Each line below is the sentence the issuing body wrote, carried with its own identifier. Nothing here interprets your result — it states what was published, for whom, and by whom.
hs-CRP
“The AHA/CDC statement gives "The cutpoints of low risk (1.0 mg/L), average risk (1.0 to 3.0 mg/L), and high risk (3.0 mg/L)", noting that "Relative risk categories (low, average, high) correspond to approximate tertiles of values"; low risk is hs-CRP below 1.0 mg/L.”
Markers of Inflammation and Cardiovascular Disease · Circulation · 2003 DOI 10.1161/01.CIR.0000052939.59093.45
“The AHA/CDC statement places average relative cardiovascular risk at an hs-CRP of 1.0 to 3.0 mg/L, which it describes as the middle of "approximate tertiles of values".”
Markers of Inflammation and Cardiovascular Disease · Circulation · 2003 DOI 10.1161/01.CIR.0000052939.59093.45
“The AHA/CDC statement places high relative cardiovascular risk at an hs-CRP above 3.0 mg/L, the upper of "approximate tertiles of values".”
Markers of Inflammation and Cardiovascular Disease · Circulation · 2003 DOI 10.1161/01.CIR.0000052939.59093.45
“The 2018 AHA/ACC multisociety cholesterol guideline lists "Elevated high-sensitivity C-reactive protein (≥2.0 mg/L)" as a risk-enhancing factor when measured.” a risk-enhancing factor, not a reference range
2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines · Circulation · 2019 DOI 10.1161/CIR.0000000000000625 · PMID 30586774
Your laboratory reads your result against its own assay, and this page does not do that for it. What is above is what a named body published and for whom; the machinery this marker reads is set out on its pathway page, and the formulas witnessed on it are below.
The machinery behind it
What raises this marker and what it goes on to move — each edge carried with its own study — is set out in full on its pathway page: Calms body-wide inflammation →
Formulas that modulate it
Each formula page names this pathway and carries the study behind its claim.
Build a combo from your panel
Open the bloodwork builder and select every marker your lab flagged — it covers the most machinery with the fewest formulas.