Estradiol
Reads: Estrogen balance
You want it in a healthy range: sufficient estrogen defends bone density and tissue integrity.
What this marker reads
Far more than a reproductive hormone — it guards bone density, vascular flexibility and skin collagen. Its withdrawal at menopause is the single largest hormonal event in human physiology, with consequences traced across five systems.
What a named body publishes
Each line below is the sentence the issuing body wrote, carried with its own identifier. Nothing here interprets your result — it states what was published, for whom, and by whom.
Estradiol
“Estradiol measured daily across the menstrual cycle in 30 healthy premenopausal women by a CDC-traceable LC-MS/MS method gave an early follicular (days -15 to -6) reference interval of 31-771 pmol/L.” females, premenopausal, early follicular phase (cycle days -15 to -6 relative to LH peak)
Estradiol reference intervals in women during the menstrual cycle, postmenopausal women and men using an LC-MS/MS method · Clinica Chimica Acta · 2019 DOI 10.1016/j.cca.2019.04.062 · PMID 30981845
“The same study's late follicular (days -5 to -1) estradiol reference interval was 104-1742 pmol/L.” females, premenopausal, late follicular phase (cycle days -5 to -1)
Estradiol reference intervals in women during the menstrual cycle, postmenopausal women and men using an LC-MS/MS method · Clinica Chimica Acta · 2019 DOI 10.1016/j.cca.2019.04.062 · PMID 30981845
“On the day of the LH peak (day 0) the estradiol reference interval was 275-2864 pmol/L.” females, premenopausal, day of LH peak (day 0)
Estradiol reference intervals in women during the menstrual cycle, postmenopausal women and men using an LC-MS/MS method · Clinica Chimica Acta · 2019 DOI 10.1016/j.cca.2019.04.062 · PMID 30981845
“The early luteal (days +1 to +4) estradiol reference interval was 95-1188 pmol/L.” females, premenopausal, early luteal phase (cycle days +1 to +4)
Estradiol reference intervals in women during the menstrual cycle, postmenopausal women and men using an LC-MS/MS method · Clinica Chimica Acta · 2019 DOI 10.1016/j.cca.2019.04.062 · PMID 30981845
“The mid luteal (days +5 to +9) estradiol reference interval was 151-1941 pmol/L.” females, premenopausal, mid luteal phase (cycle days +5 to +9)
Estradiol reference intervals in women during the menstrual cycle, postmenopausal women and men using an LC-MS/MS method · Clinica Chimica Acta · 2019 DOI 10.1016/j.cca.2019.04.062 · PMID 30981845
“The late luteal (days +10 to +14) estradiol reference interval was 39-1769 pmol/L.” females, premenopausal, late luteal phase (cycle days +10 to +14)
Estradiol reference intervals in women during the menstrual cycle, postmenopausal women and men using an LC-MS/MS method · Clinica Chimica Acta · 2019 DOI 10.1016/j.cca.2019.04.062 · PMID 30981845
“In 33 postmenopausal women the estradiol reference interval was stated as below 26 pmol/L (an upper limit only).” females, postmenopausal
Estradiol reference intervals in women during the menstrual cycle, postmenopausal women and men using an LC-MS/MS method · Clinica Chimica Acta · 2019 DOI 10.1016/j.cca.2019.04.062 · PMID 30981845
“In 64 healthy men the estradiol reference interval was 12-136 pmol/L.” males
Estradiol reference intervals in women during the menstrual cycle, postmenopausal women and men using an LC-MS/MS method · Clinica Chimica Acta · 2019 DOI 10.1016/j.cca.2019.04.062 · PMID 30981845
Your laboratory reads your result against its own assay, and this page does not do that for it. What is above is what a named body published and for whom; the machinery this marker reads is set out on its pathway page, and the formulas witnessed on it are below.
The machinery behind it
What raises this marker and what it goes on to move — each edge carried with its own study — is set out in full on its pathway page: Estrogen balance →
Formulas that modulate it
Each formula page names this pathway and carries the study behind its claim.
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