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Botanical

Perilla frutescens

Perilla
Interstellar grade B

Preclinical: Mechanistic, cell or animal evidence. No single preclinical driver opens a pathway on its own.

Appears on 6 blend pages, each linked below.

The purple shiso of Japanese kitchens: its rosmarinic acid settles the mast cell.

Traditional reading

Zi Su Ye紫苏叶Traditional Chinese medicine

The leaf was used to drive out wind-cold, settle the stomach and counter sickness from bad fish or shellfish.

Source: ShennongAlpha NMM-01W5, Chinese Pharmacopoeia 2020 | Igarashi M, Miyazaki Y. Evid Based Complement Alternat Med 2013;2013:925342

A traditional reading, held separate from the graded evidence above. It opens no pathway.

What the evidence shows

Every line below is carried on the blend page that makes the claim. Follow it to the pathway and its sources.

In a 12-week randomized, double-blind, placebo-controlled trial of 93 adults aged 55 and over, purple perilla leaf improved word recall, delayed recall and word recognition.

ALZ (Memory Preservation) →

Topped a dozen everyday fruits and vegetables at switching on the antioxidant response element, and the activity tracked to one chalcone that kept cells alive against a nerve toxin.

NRF2 Activator (Endogenous Antioxidant Induction) →

Where it appears

6 blend pages carry this ingredient. Open it and you will find this ingredient in the list.

Pathways it touches

Airway Reactivity Histamine
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