Plant

Jiaogulan

Gynostemma pentaphyllum

Interstellar grade B+

Corroborated: Human data, or animal evidence replicated by an independent laboratory. It opens a pathway only alongside an independent corroborating driver.

Appears on 13 blend pages, each linked below.

Jiaogulan reaches four steps in cultured cells: the p53 alarm, the checkpoint before division, the inflammation switch, and the tools a cell uses to loosen its grip and move through tissue.

Traditional reading

Jiao Gu Lan绞股蓝Traditional Chinese medicine / southern Chinese folk medicine

Drunk as a tea to restore strength after illness and to ease a phlegmy cough.

Source: ShennongAlpha NMM-084X, Chinese Pharmacopoeia | Mishra RN, Joshi D. Int J Res Pharm Biomed Sci 2011;2(4):1483-1499 (Bencao Gangmu 1578)

A traditional reading, held separate from the graded evidence above. It opens no pathway.

What the evidence shows

Every line below is carried on the blend page that makes the claim. Follow it to the pathway and its sources.

Jiaogulan reaches four steps in cultured cells: the p53 alarm, the checkpoint before division, the inflammation switch, and the tools a cell uses to loosen its grip and move through tissue.

ACB (Cell-Cycle Checkpoint Restraint) →

In a placebo-controlled trial Gynostemma cut abdominal fat, body weight and BMI, reversing obesogen-driven adiposity at its source.

Obesogen Blocker (Endocrine Disruptor Defense) →

Jiaogulan switched AMPK back on in the white fat of mice on a high-fat diet, more so as the amount rose.

Adipocyte Apoptosis (Mature Fat Cell Clearance) →

Jiaogulan (Gynostemma pentaphyllum) suppressed the high-fat-diet rise in C/EBP-alpha, PPAR-gamma and SREBP-1c in visceral fat.

Anti-Adipogenic (Preadipocyte Arrest) →

Early human evidence, hedged: pooled randomized human trials exist.

Triglyceride Decimator (Serum Lipid Reduction) →

In 72 chronically stressed adults, trait anxiety fell 16.8% against placebo.

Trinity (Mind Body Spirit Harmonizer) →