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Plant

Houpu magnolia

Magnolia officinalis

Houpu magnolia (Magnolia officinalis)
Interstellar grade B+

Corroborated: Human data, or animal evidence replicated by an independent laboratory. It opens a pathway only alongside an independent corroborating driver.

Appears on 9 blend pages, each linked below.

Hou Po, the magnolia bark of Chinese medicine, gives honokiol and magnolol, which soften the brain's alarm to the adrenals and help cortisol fall back.

Traditional reading

Hou Po厚朴Traditional Chinese medicine

Used to relieve a tight, full feeling in the chest and abdomen and to clear phlegm.

Source: Poivre M, Duez P. J Zhejiang Univ Sci B 2017;18(3):194-214 | ShennongAlpha nmm-01ha (Chinese Pharmacopoeia 2020)

A traditional reading, held separate from the graded evidence above. It opens no pathway.

What the evidence shows

Every line below is carried on the blend page that makes the claim. Follow it to the pathway and its sources.

Honokiol from magnolia bark cut sphere formation by oral disease's growth-seeding cells to 22% and put over half of them into programmed death; mouse growths came out 64.5% smaller.

ACB (Cell-Cycle Checkpoint Restraint) →

Substantially active against six strains, with separate work independently reporting it inhibits both the bacterium and the gastritis it causes. Two unrelated sources pointing the same way, both in cell culture.

Helico (Gastric Colonization Defense) →

Magnolia bark's honokiol and magnolol relax bronchial smooth muscle, loosening the grip a cold draft or allergen takes on the air pipe.

Lung Power (Respiratory Capacity) →

Honokiol, the biphenyl of magnolia bark, drove strong autophagy in cells and raised the autophagy marker LC3B-II in treated mice.

Autophagy Activator (Cellular Self-Renewal) →

Magnolia bark’s magnolol cut jawbone resorption, the bone-dissolving osteoclasts and the RANKL signal that summons them.

Sabretooth (Periodontal Defense) →

Where it appears

9 blend pages carry this ingredient. Open it and you will find this ingredient in the list.

Pathways it touches

HPA Axis / Cortisol Airway Reactivity Helicobacter pylori
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