Goji berry
Lycium barbarum
Reaches the abnormal prostate cells that no longer answer to hormone-blocking drugs: goji's polysaccharide fraction pushed programmed death to 41.5% and 35.5% in two such human cell lines and broke their DNA outright.
Gou Qi Zi枸杞子Traditional Chinese medicine
Taken to nourish the liver and kidneys and to brighten dim eyesight.
Source: HK PolyU Chinese Herbal Medicine Database 枸杞子 | Yao R et al. J Ethnopharmacol 2018 (Mingyi Bielu, 500 CE)
A traditional reading, held separate from the graded evidence above. It opens no pathway.
What the evidence shows
Every line below is carried on the blend page that makes the claim. Follow it to the pathway and its sources.
Its polysaccharides extend lifespan and stress resistance in roundworms through the SIRT1 and FOXO routes, switching on the worm's NRF2 and heat-shock responses.
Wolfberry's polysaccharides settle the inflammatory chatter in kidney tissue, damping the NF-kB messenger that sets the whole cascade in motion.
Goji's zeaxanthin dipalmitate is among the richest dietary sources of the pigment, and it banks in the macula as a filter against glare.
The long sugar chains of the goji berry raise SIRT1 in animals across eye, nerve and metabolic models.
Early human evidence, hedged: pooled randomized human trials exist.
Tested against placebo in adolescents with low mood and in a well-being trial; works on BDNF and serotonin.
Where it appears
8 blend pages carry this ingredient. Open it and you will find this ingredient in the list.
- ACB (Cell-Cycle Checkpoint Restraint)
- Female Fertility (Oocyte Competence)
- Hormesis (Adaptive Stress Conditioning)
- Jing Force (Kidney Restoration)
- Ocular (Retinal & Macular Support)
- SIRT1 Activator (Caloric-Restriction Mimetic)
- Triglyceride Decimator (Serum Lipid Reduction)
- Trinity (Mind Body Spirit Harmonizer)